Fat part of biotech trade is seen

While specific U.S. biotech’s are held in client portfolios, the broader sector has seen the ‘fat part’ of the trade.

An extreme low in the S&P Biotech ETF (XBI) was mentioned in the April 6, 2025 edition of my Macro Extremes weekly note.

and an overbought extreme was highlighted in yesterdays edition.

For now, ~37% over 6 months will do.

I’ll leave the next 10% for someone else.

October 6, 2025

rob@karriasset.com.au

Biotech clouds are not clearing

My note from 1 month ago called for a bounce in biotech prices but re-iterated my view that I still expect prices to ladder their way lower.

In that note, I referenced the iShares Biotech ETF (IBB).

And so, from the day of my note’s release (November 19, 2024), it did commence its climb, eventually rising 7.5% and recovering 50% of the recent decline.

Since then, the IBB ETF has fallen again, erasing those gains and has since making a new ‘lower low’.

And I’m still calling IBB down to the $100 mark. It is $131 today.

December 20, 2024

rob@karriasset.com.au

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Dark clouds for biotech

Last week’s abrupt decline in the U.S. #biotech indices look like the beginning of a larger decline.

It could be a dark winter while political machinations sort themselves out.

For some reference, while the iShares Biotech ETF #IBB will likely bounce in the near term, I’ll look for it to eventually trade down slightly below the $100 mark.

November 19, 2024

rob@karriasset.com.au

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